Fig. 1. Binding interaction of acarbose, 6-amino-1,3,5-triazine-2,4(1H,3H)-dione, and 1-(2-hydroxy-5-methylphenyl)-ethanone in the active site pocket of (A) α-amylase and (B) α-glucosidase. A1, A2, and A3 amino acids of α-amylase are surrounded by acarbose, 6-amino-1,3,5-triazine-2,4(1H,3H)-dione, and 1-(2-hydroxy-5-methylphenyl)-ethanone, respectively. B1, B2, and B3 amino acids of α-glucosidase are surrounded by acarbose, 6-amino-1,3,5-triazine-2,4(1H,3H)-dione, and 1-(2-hydroxy-5-methylphenyl)-ethanone, respectively. The green dotted lines indicate hydrogen bonds.
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