Fig. 3. (A) Dose-effect curves of nicotinamide (NAM), Agastache rugosa extract (AR), and NAM and AR (NAM-AR) mixture with 6:4 combination ratio on skin fibroblast viability. (B) Isobologram curves of NAM, AR, and NAM-AR mixture with 6:4 combination ratio. (C) Median effect plot of NAM, AR, and NAM-AR mixture with 6:4 combination ratio. (D) Combination index (CI) plot.
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