Meta-regression of plant sterols/stanols supplementation dose and duration on lipid profile using the apolipoprotein E groups
Apolipoprotein E group | Outcome | Covariate | No. of studies | Coefficient | 95% confidence interval | |
---|---|---|---|---|---|---|
E3 | TC | Dose Duration |
9 | —0.412567 —0.005806 |
—0.854252 to 0.029118 —0.068577 to 0.056964 |
0.0671 0.8561 |
E4 | TC | Dose Duration |
9 | —0.670363 —0.056443 |
—1.285657 to —0.055069 0.045245 to 0.032234 |
0.0327 0.2122 |
E3 | LDL | Dose Duration |
10 | —0.160048 —0.031707 |
—0.432956 to 0.112861 —0.089536 to 0.026121 |
0.2504 0.2825 |
E4 | LDL | Dose Duration |
10 | —0.339041 —0.088027 |
—0.722386 to 0.044303 —0.154690 to —0.021364 |
0.0830 0.0097 |
E3 | HDL | Dose Duration |
7 | 0.231371 0.020791 |
—0.173639 to 0.636380 —0.024081 to 0.065664 |
0.2629 0.3638 |
E4 | HDL | Dose Duration |
7 | 0.018633 —0.003348 |
—0.082982 to 0.120249 —0.022022 to 0.015325 |
0.7193 0.7253 |
E3 | TG | Dose Duration |
7 | 0.050605 —0.021778 |
—0.072949 to 0.174160 —0.065191 to 0.021635 |
0.4221 0.3255 |
E4 | TG | Dose Duration |
7 | —0.004206 —0.019614 |
—0.189003 to 0.180591 —0.075335 to 0.036107 |
0.9644 0.4903 |
TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides.