Fig. 5. Light photomicrographs (45× magnification) of rat femur bone sections from different experimental groups: (A) normal control, (B) negative control, (C) 200 mg/kg of metformin, (D) 100 mg/kg of petroleum ether extracts of Brassica oleracea (PEE), (E) 200 mg/kg of PEE, (F) 400 mg/kg of PEE, (G) 100 mg/kg of ethanol extract of B. oleracea (EE), (H) 200 mg/kg of EE, (I) 400 mg/kg of EE, (J) 100 mg/kg of aqueous extract of B. oleracea (AE), (K) 200 mg/kg of AE, and (L) 400 mg/kg of AE. The arrows indicate the bone stucture. (A) The normal control group showed original microstructure in thickness. (B) Negative control showed destruction of the medullary cavity and decreased femoral thickness. (F, I, K, and L) Improvement in femur bones was observed, especially the trabeculae and Haversian canal.

Prev Nutr Food Sci 2022;27:50~62 https://doi.org/10.3746/pnf.2022.27.1.50