Fig. 4. Light photomicrographs (45× magnification) of rat pancreas sections from different experimental groups: (A) normal control, (B) negative control, (C) 200 mg/kg of metformin, (D) 100 mg/kg of petroleum ether extracts of Brassica oleracea (PEE), (E) 200 mg/kg of PEE, (F) 400 mg/kg of PEE, (G) 100 mg/kg of ethanol extract of B. oleracea (EE), (H) 200 mg/kg of EE, (I) 400 mg/kg of EE, (J) 100 mg/kg of aqueous extract of B. oleracea (AE), (K) 200 mg/kg of AE, and (L) 400 mg/kg of AE. The arrows indicate the appearance of pancreas. (A) The normal control group showed normal architecture of the pancreas. (B) The negative control group showed pathological changes of both endocrine and exocrine components. Acinar and β cells of the pancreas were damaged and shrunken in size. (H∼L) Pancreatic β cells showed remarkable improvement and observed regeneration of islets of Langerhans.

Prev Nutr Food Sci 2022;27:50~62 https://doi.org/10.3746/pnf.2022.27.1.50