Effect of various extracts of
Group | TNF-α | IL-6 |
---|---|---|
Normal control | 19.64±1.21 |
106.39±10.38 |
Negative control | 58.20±4.81 | 137.63±11.45 |
DM+metformin (200 mg/kg) | 22.16±2.16 |
110.90±10.81 |
DM+PEE (100 mg/kg) | 59.46±4.96 | 140.55±12.52 |
DM+PEE (200 mg/kg) | 56.21±4.17 | 130.38±8.11 |
DM+PEE (400 mg/kg) | 50.38±3.63 |
127.31±9.20 |
DM+EE (100 mg/kg) | 52.25±3.55 | 137.70±8.91 |
DM+EE (200 mg/kg) | 45.22±4.02 |
126.82±9.87 |
DM+EE (400 mg/kg) | 30.06±2.10 |
122.35±7.04 |
DM+AE (100 mg/kg) | 35.39±2.96 |
120.69±6.45 |
DM+AE (200 mg/kg) | 28.84±1.93 |
119.36±8.08 |
DM+AE (400 mg/kg) | 24.93±1.21 |
113.60±6.30 |
The values are presented as mean±SD for each group (n=8).
Statistical analysis of data was performed using one-way ANOVA followed by Tukey’s multiple range test.
*
TNF-α, tumor necrosis factor-αlpha; IL-6, interleukin-6; DM, type 2 diabetes mellitus; PEE, petroleum ether extract; EE, ethanol extract; AE, aqueous extract.