Fig. 3. Light photomicrographs (45× magnification) of rat brain sections from different experimental groups: (A) normal control, (B) negative control, (C) 200 mg/kg of metformin, (D) 100 mg/kg of petroleum ether extracts of Brassica oleracea (PEE), (E) 200 mg/kg of PEE, (F) 400 mg/kg of PEE, (G) 100 mg/kg of ethanol extract of B. oleracea (EE), (H) 200 mg/kg of EE, (I) 400 mg/kg of EE, (J) 100 mg/kg of aqueous extract of B. oleracea (AE), (K) 200 mg/kg of AE, and (L) 400 mg/kg of AE. The arrows indicate neuron cells. (A) The normal control group showed a normal appearance in the cerebral cortex structure. (B, D, E, and G) Negative control and treated groups showed a loss of internal structure. Distorted pyramidal layers revealed degenerative changes and observed shrinkage in pyramidal cells. (C, F, and H∼L) Remarkable improvement in the regeneration of glial cells and no inflammatory changes were observed. The pyramidal layer showed the reappearance of normal pyramidal cells.

Prev Nutr Food Sci 2022;27:50~62 https://doi.org/10.3746/pnf.2022.27.1.50