Table. 1.

Table. 1. Table 1

Serum glucose level after treatment with various extracts of Brassica oleracea L. at different intervals in rats with type 2 diabetes mellitus (unit: mg/dL)

Group	0 day	7th day	14th day	21st day	42nd day
Normal control	87.45±6.16^***	83.11±7.75^***	81.58±5.13^***	89.33±9.11^***	80.65±3.17^***
Negative control	345.15±0.77	341.40±28.65	355.42±32.19	358.17±37.81	348.60±43.98
DM+metformin (200 mg/kg)	355.18±51.79	279.72±38.16^*###	183.17±22.58^***###	99.05±12.19^***###	75.27±4.13^***###
DM+PEE (100 mg/kg)	362.11±33.68	344.33±46.24	347.71±32.12	326.21±77.11^ns	299.13±38.57
DM+PEE (200 mg/kg)	387.76±46.17	318.17±39.75^##	298.21±12.29^***###	255.71±14.78^***###	221.17±22.11^***###
DM+PEE (400 mg/kg)	371.43±43.18	302.13±24.19^*#	243.11±26.11^***###	197.16±23.18^***###	143.44±23.77^***###
DM+EE (100 mg/kg)	362.8±12.84	345.13±44.12	325.16±17.18	291.27±43.28^#	253.65±40.02^***###
DM+EE (200 mg/kg)	385.54±30.19	338.16±49.11	287.61±55.14^*##	233.14±29.28^***###	184.24±28.18^***###
DM+EE (400 mg/kg)	377.1±29.31	303.11±13.48^*#	232.11±41.78^***###	186.19±42.68^***###	137.18±47.14^***###
DM+AE (100 mg/kg)	373.23±40.11	355.03±39.19	296.21±33.78^*##	220.29±15.01^***###	201.09±17.03^***###
DM+AE (200 mg/kg)	393.32±14.48	296.14±40.23^*###	212.28±17.16^***###	154.71±14.78^*###	128.14±15.18^***###
DM+AE (400 mg/kg)	378.50±51.23	256.21±27.19^***###	201.17±64.16^**###	152.41±29.12^***###	123.14±23.14^***###

The values are presented as mean±SD for each group (n=8).

Statistical analysis of data was performed using one-way ANOVA followed by Tukey’s multiple range test.

*P<0.05, **P<0.01, and ***P<0.001 compared with negative control group and ^#P<0.05, ^##P<0.01, and ^###P<0.001 compared with day 0.

DM, type 2 diabetes mellitus; PEE, petroleum ether extract; EE, ethanol extract; AE, aqueous extract; ns, not significant compared with control group.

Prev Nutr Food Sci 2022;27:50~62 https://doi.org/10.3746/pnf.2022.27.1.50