Fig. 8. Effect of test substances on collagenase, hydroxyproline, hyaluronic acid, and ceramide levels. Eight groups (G1∼G8) in total were employed for the experiment. G1 was control and G2 was sham control. G3∼G8 were induced with ultraviolet-irradiation; G3 was path control (no treatment). G4 was standard drug (hyaluronic acid) treated. G5 (low dose) and G6 (high dose) were treated with test compound A; G7 (low dose) and G8 (high dose) were treated with test compound B. After 42 days of treatment, the levels of collagenase, hydroxyproline, hyaluronic acid, and ceramide levels were measured by ELISA kit. The plasma from the treated and untreated animals was used for analysis as per the kit protocol. The values were expressed in mean±SEM. *P<0.05, **P<0.01, and ***P<0.001 was considered statistically significant when compared to group 3 values.

Prev Nutr Food Sci 2021;26:425~433 https://doi.org/10.3746/pnf.2021.26.4.425