Fig. 5. Effect of test substances on transepidermal water loss (TEWL). Eight groups (G1∼G8) in total were employed for the experiment. G1 was control and G2 was sham control. G3∼G8 were induced with ultraviolet-irradiation; G3 was path control (no treatment). G4 was standard drug (hyaluronic acid) treated. G5 (low dose) and G6 (high dose) were treated with test compound A; G7 (low dose) and G8 (high dose) were treated with test compound B. After 42 days of treatment the TEWL score was measured using corneometer. The TEWL score is digitally generated by measuring the dielectric properties of the skin. The values were expressed in mean±SEM. ***P<0.001 was considered statistically significant when compared to group 3 values.

Prev Nutr Food Sci 2021;26:425~433 https://doi.org/10.3746/pnf.2021.26.4.425