Fig. 3. Effects of Chrysanthemum morifolium Ramat. extract (CME) and isochlorogenic acid A (IcA) on body weight, skeletal muscle mass, volume, and cross-sectional area of myofibers. (A) Measured body weight and (B) masses of gastrocnemius, soleus, tibialis anterior (TA), and extensor digitorum longus (EDL), normalized to body weight. (C and D) Muscle volume of hindlimb calculated using micro-computed tomography, and (E and F) cross-sectional area of muscle fiber evaluated via H&E staining (×200). Data are presented as mean±standard deviation. Group differences were assessed using Duncan’s multiple range test. ##P<0.01 [young group vs. middle-aged (MA) group] and *P<0.05 and **P<0.01 (MA group vs. CME and IcA groups).
© Prev. Nutr. Food Sci.