Fig. 1. Change in the body weight of Sprague-Dawley rats treated orally with DNF-10 for the determination of acute and subacute toxicity. Acute toxicity was observed for 14 days after the single administration of 5,000 mg/kg DNF-10. Subacute toxicity was observed for 14 days after the repeated administration of 1,000 mg/kg DNF-10 for 90 days. Values are mean±SEM for each group. Significant differences at *P<0.05 by the Student’s t-test.
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