Table. 3.

Table. 3. Table 3

Haematological parameters of Sprague-Dawley rats treated orally with DNF-10 for the evaluation of acute and subacute toxicity

Haematological parameters	Acute toxicity			Subacute toxicity

	Control	DNF-10		Control	DNF-10
Female
WBC (10³/μL)	6.78±0.44^ns	5.73±0.69		6.87±0.42	5.55±0.19*
RBC (10⁶/μL)	8.30±0.16	7.81±0.10*		8.52±0.16	7.99±0.12*
Hb (g/L)	17.93±0.31	16.68±0.29*		15.74±0.27^ns	15.17±0.14
Hct (%)	54.15±1.30^ns	51.90±0.77		53.97±1.02	50.96±0.60*
MCV (fL)	65.24±0.57^ns	66.50±0.55		63.37±0.34^ns	63.82±0.53
MCH (pg)	21.63±0.24^ns	21.36±0.14		18.52±0.33^ns	19.01±0.18
MCHC (g/dL)	33.16±0.48^ns	32.13±0.38		29.23±0.45^ns	29.77±0.09
Male
WBC (10³/μL)	8.83±0.59^ns	10.83±0.99		9.58±0.85^ns	12.17±1.19
RBC (10⁶/μL)	8.57±0.30^ns	7.88±0.30		9.32±0.09^ns	9.37±0.22
Hb (g/L)	17.90±0.47^ns	16.86±0.65		16.43±0.26^ns	16.68±0.40
Hct (%)	59.91±2.01^ns	56.45±2.12		58.06±0.76^ns	58.41±1.53
MCV (fL)	69.96±0.56^ns	71.73±0.85		62.31±0.47^ns	62.31±0.55
MCH (pg)	20.96±0.38^ns	21.48±0.58		17.66±0.25^ns	17.80±0.18
MCHC (g/dL)	29.96±0.47^ns	29.91±0.55		28.32±0.24^ns	28.58±0.20

Values are mean±SEM for each group.

Significant differences at *P<0.05 by Student’s t-test.

All abbreviations in Table 3 are described in MATERIALS AND METHODS.

^nsNot significant.

Prev Nutr Food Sci 2021;26:75~81 https://doi.org/10.3746/pnf.2021.26.1.75

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